Molecular glues are rapidly emerging as a transformative modality in drug discovery, enabling novel mechanisms to modulate protein function through stabilization of protein–protein interactions. Yet discovering synthetic molecular glues de novo remains a major challenge, particularly due to the need to identify compounds that both engage a target and promote cooperative ternary complex formation.
3rd Biophysics for Drug Discovery Summit 2026
ZoBio is excited to attend TFMED 2026, a four-day transdisciplinary conference dedicated to next-generation therapeutic modalities, including molecular glues, PROTACs, nucleic acid-based therapies, and cell-based approaches.
The meeting brings together researchers, clinicians, and industry experts, offering in-depth scientific sessions, direct interaction with leading specialists, and valuable opportunities for networking and collaboration, with a strong focus on early-career scientists.
Therapeutic Frontiers in Medicine, Mechanisms and Modalities
ZoBio is excited to attend TFMED 2026, a four-day transdisciplinary conference dedicated to next-generation therapeutic modalities, including molecular glues, PROTACs, nucleic acid-based therapies, and cell-based approaches.
The meeting brings together researchers, clinicians, and industry experts, offering in-depth scientific sessions, direct interaction with leading specialists, and valuable opportunities for networking and collaboration, with a strong focus on early-career scientists.
Covalent Screening Guide: Unlock New Possibilities in Drug Discovery
Covalent screening has become a powerful strategy in modern small-molecule drug discovery, enabling researchers to tackle targets that are often difficult to address using traditional approaches. Once viewed as high risk, covalent strategies are now widely recognized for their ability to deliver potent, selective, and long-lasting therapeutics.
Unlike conventional screening methods, covalent approaches rely on more than transient binding interactions. They require a carefully tuned balance between reversible target recognition and covalent bond…