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Expanding Isotopic Labeling in Mammalian Expression: Pushing the Boundaries on NMR Studies of Hard-to-Express Proteins
ZoBio is excited to expand its exclusive capability for making complex protein samples for drug discovery with 13C-methyl MILV isotopic labeling during HEK293 mammalian…
Lipids Make a Difference: Local Collaboration Advances Drug Discovery for Membrane Proteins
Membrane proteins are without a doubt an important drug target: about 60% of all confirmed drug targets are located on the cell surface. However, studying these proteins in vitro has long been challenging due to…
SMR Meeting: Molecular Glues
In person Molecular glues and targeted protein degraders are revolutionizing the field of drug discovery, offering promising solutions for a range of diseases, including cancer, infectious, inflammatory, and neurodegenerative diseases. These innovative therapies are particularly beneficial for targeting previously “undruggable” pathogenic proteins. The recent emergence of the ‘molecular glue’ class of protein degraders is paving…