Drug discovery doesn’t sleep, and neither does our SPR (Surface Plasmon Resonance) team. While the Assay Group takes a well-deserved weekend break and goes for dinner tonight, our relentless SPR team is tirelessly screening compounds, revealing critical insights that help drive discovery forward.
Meet the Team:
Each of our SPR machines brings unique strengths to the lab, earning their names and personalities for how they support our research. These workhorses are the true heroes of our lab, capturing precise data…
32nd Protein Structure Determination in Industry meeting
In person Starting from Sunday, November 10th, the ZoBio team participated in the 32nd Protein Structure Determination in Industry meeting, which was held at the Novotel Paris Centre Tour Eiffel in Paris, France. This year’s meeting was organized jointly by SERVIER and Synchrotron SOLEIL, with support from Hg3 Conferences. The scientific talks focused on the…
Molecular Glues Discovery
Molecular glues have emerged as an exciting new class of agents in drug discovery, offering a novel mechanism to modulate protein function, both as protein degraders and for other therapeutic targets. Unlike traditional drugs that inhibit or block protein activity, molecular glues enhance or induce new protein-protein interactions (PPIs), allowing them to activate biological pathways rather than suppressing them. For instance, the natural compound Rapamycin has been used as an immunosuppressant for decades. It binds at the interface of mTOR and FKBP12 and increases the interaction between these two proteins…
Isotopic Labeling in Mammalian Expression: The Missing Link for NMR Studies of Hard-to-Express Proteins
ZoBio is excited to introduce a new exclusive capability for making complex protein samples for drug discovery: isotopic labeling during mammalian expression. This ability provides the missing link between…