NMR in Target Driven Drug Discovery: Why Not?
NMR is a powerful and information rich tool that can provide critical information at many stages of the pre-clinical drug discovery process.
In a recent publication ZoBio scientists discuss a number of examples in which relatively simple NMR experiments routinely provided them with data critical to the setup of new programs, interpretation of biophysical and biochemical data and elucidation of structural information describing the protein–small molecule interaction. In this article examples from the very early stages of target preparation and hit discovery are reported, but we also show how NMR offers the potential to observe protein–ligand interactions and thereby contribute structural information in multiple settings.
Our NMR team is ready to make an impact on your drug discovery campaign as well.