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Modulation of protein-protein interactions (PPIs) with molecular glues is an emerging strategy in drug discovery, offering potential solutions for targeting ‘hard to drug’ protein classes. On June 18th one of our scientists, Pim de Vink, shared his experience and discussed common trends with fellow drug discovery scientists during the Cytiva webinar.
In his presentation Pim outlined a series of biophysical assay setups specifically developed for the screening and validation of new molecular glues using a fragment-based approach.