Upcoming events
EFMC-ACSMEDI Medicinal Chemistry Frontiers 2026
In person
At this year’s EFMC Medicinal Chemistry Frontiers conference, Marta Carneiro will present a poster dedicated to one of the most exciting and challenging areas in drug discovery: molecular glues.
The poster “Biophysics-driven Molecular Glue Discovery” addresses a central question in the field: how do we reliably discover and characterize molecular glues, especially when traditional screening approaches fall short?
Rather than relying solely on affinity-driven methods, the poster highlights a cooperativity-focused biophysical framework designed to capture the unique behaviour of ternary systems. This shift in perspective is particularly important in molecular glue discovery, where functional activity emerges not just from binding, but from the ability to stabilize productive protein-protein interactions.
During the poster session, Marta will share selected case studies illustrating how fragment-based approaches and tailored biophysical assays can reveal glue-like behaviour that might otherwise be missed. These examples also highlight the challenges of working with multi-component systems, where subtle changes in cooperativity can make the difference between inactive binders and functional molecular glues.
We look forward to engaging with colleagues to explore how our biophysical approaches can add value to ongoing molecular glue discovery programs!
RICT 2026
In person
ZoBio will be attending the upcoming RICT conference in Paris, where we will showcase our biophysics-driven approaches to early-stage drug discovery.
Our colleague Anne-Sophie Huart, will present a poster highlighting how flexible biophysical strategies can be applied across a broad range of discovery challenges.
The poster showcases how tailored biophysical workflows can:
- Support hit identification across multiple modalities
- Enable deeper mechanistic understanding of interactions
- Improve confidence in early-stage validation strategies
- Adapt to complex or unconventional drug discovery targets
Let’s Talk Biophysics in Paris!
Past events
SLAS Europe 2026
In person
Molecular glues are rapidly emerging as a transformative modality in drug discovery, enabling novel mechanisms to modulate protein function through stabilization of protein–protein interactions. Yet discovering synthetic molecular glues de novo remains a major challenge, particularly due to the need to identify compounds that both engage a target and promote cooperative ternary complex formation.
At SLAS Europe, our colleague Pim de Vink presented a biophysics-driven framework for molecular glue discovery across challenging targets, with a particular focus on cooperativity as a guiding principle in screening and characterization strategies.
By focusing directly on ternary complex formation and cooperativity, this framework aims to lower the barrier to discovering next-generation molecular glue therapeutics.
3rd Biophysics for Drug Discovery Summit 2026
In person
ZoBio attended the 3rd Biophysics for Drug Discovery Summit 2026 in Boston, a unique, industry-focused forum dedicated exclusively to biophysics. Through case studies, panel discussions, and interactive exchanges, the summit highlights how emerging biophysical technologies are shaping predictive pipelines and accelerating drug discovery.
Marta Carneiro presented the poster: “Tailor-made Biophysics – A versatile toolkit for discovery and validation”, which attracted a lot of attention during the meeting.
Marta shared selected case studies demonstrating how biophysical approaches can address diverse discovery challenges – from fragment-based screening for molecular glues, to profiling covalent compounds and antibody – antigen interactions, as well as generating structural models when X-ray crystallography reaches its limits.
Curious to see how these approaches can support complex discovery programs? Download the poster to explore the case studies and insights in more detail.
Download the Poster: Tailor Made Biophysics
Therapeutic Frontiers in Medicine, Mechanisms and Modalities
In person
ZoBio was attending TFMED 2026, a four-day transdisciplinary conference dedicated to next-generation therapeutic modalities, including molecular glues, PROTACs, nucleic acid-based therapies, and cell-based approaches.
The meeting brought together researchers, clinicians, and industry experts, offering in-depth scientific sessions, direct interaction with leading specialists, and valuable opportunities for networking and collaboration, with a strong focus on early-career scientists.
Anna Belorusova presented a flash talk and poster titled: “SPR Workflows for Molecular Glue Hit Discovery.”
In her presentation, she highlighted how ZoBio supports molecular glue discovery through dedicated Surface Plasmon Resonance (SPR) workflows, complemented by a suite of orthogonal biophysical techniques. This integrated platform enables direct assessment of protein–protein interactions, supports fragment screening and validation, and provides insights into the likelihood of identifying molecular glues for specific target pairs.
By combining multiple biophysical approaches, we deliver robust characterization and mechanistic understanding of hits, helping to de-risk early-stage discovery and accelerate progress toward challenging targets