30 JUNE 2021
Targeting both RNA and the proteins that interact with it has become one of the hottest new areas in drug discovery. Biotechs such as Storm Therapeutics, 28-7, Gotham Therapeutics and Accent Therapeutics amongst many others, are all developing small molecule inhibitors of misregulated epigenetic processes.
On Wednesday, June 30th ZoBio organized together with Cambridge Healthtech Institute the webinar: “Epitranscriptomics and Disease: The Role of RNA Modification in the Life Cycle of the Cell”. During the webinar two of the top experts in the field: Samie R. Jaffrey, the Greenberg-Starr Professor in the Department of Pharmacology at the Weill Cornell Medical College and Sebastian Leidel, Professor in the Department of Chemistry, Biochemistry and Pharmaceutical Sciences (DCBP) University of Bern highlighted an exciting developments on RNA modifications and epitranscriptomics.
Both key opinion leaders shared their insights into the mechanisms of epitranscriptomics and its relationship to disease, in particular oncology. They described their latest findings on important targets and the biological outcome of inhibiting them. In addition, ZoBio shared a case study on development of small molecule inhibitors of an epitranscriptomic target.
18-20 MAY 2021
ZoBio contributes since the start of Cambridge Healthtech Institute’s (CHI) Drug Discovery Chemistry to this dynamic conference for medicinal chemists working in pharma and biotech. Focused on discovery and optimization challenges of small molecule drug candidates, this event provides many exciting opportunities for scientists.
On Tuesday 18 May Stijn Gremmen, Head of Chemistry at ZoBio gave the talk ‘Fragments with a Future – a Path Towards Tractable Chemical Series’ and presented the learnings from multiple fragment hit to lead projects. The importance of a holistic view of fragment chemistry, orthogonal biophysical techniques and structural biology for deriving novel, tractable chemical series was illustrated through examples.
Afterwards, together with other speakers Stijn participated in an interesting and educational Q&A session.
19 APRIL 2021
On the 19th of April 2021, ZoBio participated in the annual CDL-LIFE Career Evening. This event connects bachelor-and master students who are looking for an internship or graduation position to the companies within the life science sector.
During the virtual meeting, a variety of companies introduced their organizations. After short presentations students had the opportunity to get in touch with representatives of the companies and receive detailed information about career opportunities.