Marta Carneiro, Head of Structural Biology at ZoBio, presented the lecture ‘NMR in target driven drug discovery: why not?’ on Wednesday 25 November 2020. Marta has discussed several examples of how ZoBio uses NMR in various ways to streamline the discovery process and reduce downstream attrition. This talk was a part of the Drug Discovery/Development session of the ICMRBS Early Career Researcher Webinar Series. The webinars are specifically meant for early researchers working on magnetic resonance in biological systems, but also for more senior scientists that may be interested in information about different NMR approaches in drug discovery.
As in the previous years ZoBio participated as a sponsor in Discovery on Target, the industry’s preeminent event on novel drug targets and technologies for drug discovery professionals. The conference highlighted advances in current and emerging “hot” targets and technologies, as well as target validation strategies for the discovery and development of novel therapeutic agents, ranging from biologics to small molecules.
Gregg Siegal presented the lecture: ‘Targeting RNA Readers’ on Wednesday September 16. In his presentation Gregg has shared insights of a developing inhibitors of YTHDF2, a protein that selectively recognized 6 methyl-adenosine in mRNA thereby regulates protein expression. Results from fragment screening and hit evolution campaign were presented.