{"id":3095,"date":"2021-07-29T15:41:04","date_gmt":"2021-07-29T15:41:04","guid":{"rendered":"https:\/\/zobio.com\/?p=3095"},"modified":"2021-11-01T13:23:54","modified_gmt":"2021-11-01T13:23:54","slug":"scientist-in-protein-engineering-production-2","status":"publish","type":"post","link":"https:\/\/zobio.com\/online\/geen-categorie\/scientist-in-protein-engineering-production-2\/","title":{"rendered":"Scientist in Protein Engineering & Production (PhD)"},"content":{"rendered":"
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Scientist in Protein Engineering & Production (PhD)<\/h1><\/div><\/div>
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29 JULY 2021<\/p>\n<\/div>\n<\/div><\/div><\/div>

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ZoBio (www.zobio.com<\/a>) was founded in 2004 and is located in Leiden, Netherlands. We offer innovative research services in the field of small-molecule drug discovery to the pharmaceutical and biotech industries. Our international team of 33 people covers four fields of expertise: Protein Engineering and Production, Assay Development and Screening, Structural Biology, and Medicinal Chemistry.<\/p>\n

Currently we are looking for a motivated, talented and trustworthy individual that can strengthen our Protein Engineering & Production team<\/strong> within ZoBio. This team currently consists of 7 talented individuals (4 PhD and 3 MSc\/BSc level) and has access to a variety of state-of-the-art equipment for expression in E. coli, purification and characterization of pharmaceutically relevant and challenging protein constructs: 4 AKTAs\/BioRad, SEC-MALS, Prometheus Panta (NanoDSF\/DLS), SDS-PAGE and gel analysis systems. Our chromatography systems are customized to provide high throughput purification for multiple proteins at one go at milligram scale. The team is involved in establishing innovative proprietary technologies for protein construct design, protein expression (E. coli, both in rich as well as isotope labeled minimal media) and protein purification to obtain biophysical grade pure protein constructs for biophysical studies in structure-based drug discovery (SPR, NMR, Cryo-EM and X-ray).<\/p>\n

\u00a0<\/em><\/strong>TASKS & RESPONSIBILITIES <\/em><\/strong><\/p>\n

The advertised position primarily concerns protein production of a variety of pharmaceutically relevant proteins. Emphasis will be on the expression side (screen, scale-up with fermenters, other host systems), to support downstream small fragment screening and structural biology activities in ZoBio. As a member of the protein engineering and production group, you will work mainly in the laboratory and in close collaboration with the assay development and structural biology groups.<\/p>\n

REQUIREMENTS<\/em><\/strong><\/p>\n