{"id":2125,"date":"2020-10-01T07:40:58","date_gmt":"2020-10-01T07:40:58","guid":{"rendered":"https:\/\/zobio.com\/?p=2125"},"modified":"2021-01-06T08:31:14","modified_gmt":"2021-01-06T08:31:14","slug":"nmr-in-target-driven-drug-discovery-why-not-new-publication-of-zobio-scientists-2","status":"publish","type":"post","link":"https:\/\/zobio.com\/online\/news\/nmr-in-target-driven-drug-discovery-why-not-new-publication-of-zobio-scientists-2\/","title":{"rendered":"NMR in Target Driven Drug Discovery: Why Not?"},"content":{"rendered":"<div id=\"pl-2125\"  class=\"panel-layout\" ><div id=\"pg-2125-0\"  class=\"panel-grid panel-has-style\" ><div class=\"panel-row-style panel-row-style-for-2125-0\" ><div id=\"pgc-2125-0-0\"  class=\"panel-grid-cell\" ><div id=\"panel-2125-0-0-0\" class=\"so-panel widget widget_sow-editor panel-first-child panel-last-child\" data-index=\"0\" ><div class=\"with-icon panel-widget-style panel-widget-style-for-2125-0-0-0\" ><div\n\t\t\t\n\t\t\tclass=\"so-widget-sow-editor so-widget-sow-editor-base\"\n\t\t\t\n\t\t><h2 class=\"widget-title\">NMR in Target Driven Drug Discovery: Why Not?<\/h2>\n<div class=\"siteorigin-widget-tinymce textwidget\">\n\t<p>NMR is a powerful and information rich tool that can provide critical information at many stages of the pre-clinical drug discovery process.<\/p>\n<p>In a recent <a href=\"https:\/\/link.springer.com\/article\/10.1007\/s10858-020-00343-9#Sec1\" target=\"_blank\" rel=\"noopener noreferrer\">publication<\/a> ZoBio scientists discuss a number of examples in which relatively simple NMR experiments routinely provided them with data critical to the setup of new programs, interpretation of biophysical and biochemical data and elucidation of structural information describing the protein\u2013small molecule interaction. In this article examples from the very early stages of target preparation and hit discovery are reported, but we also show how NMR offers the potential to observe protein\u2013ligand interactions and thereby contribute structural information in multiple settings.<\/p>\n<p>Our NMR team is ready to make an impact on your drug discovery campaign as well.<\/p>\n<p><i>\u00a0<\/i><\/p>\n<p>&nbsp;<\/p>\n<\/div>\n<\/div><\/div><\/div><\/div><\/div><\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>NMR is a powerful and information rich tool that can provide critical information at many stages of the pre-clinical drug discovery process.<br \/>\nIn a recent publication ZoBio scientists discuss a number of examples&#8230;<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"gpsa_enabled":false,"gpsa_required_form_ids":[],"gpsa_require_unique_form_submission":false,"gpsa_access_behavior":"show_message","gpsa_form_redirect_path":"","gpsa_requires_access_message":"","gpsa_access":[],"gpsa_content_loading_message":"","footnotes":""},"categories":[3],"tags":[9],"class_list":["post-2125","post","type-post","status-publish","format-standard","hentry","category-news","tag-discovery"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.1.1 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>NMR in Target Driven Drug Discovery: Why Not? - ZoBio - Drug Discovery Technology<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/zobio.com\/online\/news\/nmr-in-target-driven-drug-discovery-why-not-new-publication-of-zobio-scientists-2\/\" \/>\n<meta property=\"og:locale\" content=\"en_GB\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"NMR in Target Driven Drug Discovery: Why Not? - ZoBio - Drug Discovery Technology\" \/>\n<meta property=\"og:description\" content=\"NMR is a powerful and information rich tool that can provide critical information at many stages of the pre-clinical drug discovery process. In a recent publication ZoBio scientists discuss a number of examples...\" \/>\n<meta property=\"og:url\" content=\"https:\/\/zobio.com\/online\/news\/nmr-in-target-driven-drug-discovery-why-not-new-publication-of-zobio-scientists-2\/\" \/>\n<meta property=\"og:site_name\" content=\"ZoBio - Drug Discovery Technology\" \/>\n<meta property=\"article:published_time\" content=\"2020-10-01T07:40:58+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2021-01-06T08:31:14+00:00\" \/>\n<meta name=\"author\" content=\"Content manager ~KB\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Content manager ~KB\" \/>\n\t<meta name=\"twitter:label2\" content=\"Estimated reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/zobio.com\/online\/news\/nmr-in-target-driven-drug-discovery-why-not-new-publication-of-zobio-scientists-2\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/zobio.com\/online\/news\/nmr-in-target-driven-drug-discovery-why-not-new-publication-of-zobio-scientists-2\/\"},\"author\":{\"name\":\"Content manager ~KB\",\"@id\":\"https:\/\/zobio.com\/online\/#\/schema\/person\/fcdd542fb16960e243f01d731e59d707\"},\"headline\":\"NMR in Target Driven Drug Discovery: Why Not?\",\"datePublished\":\"2020-10-01T07:40:58+00:00\",\"dateModified\":\"2021-01-06T08:31:14+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/zobio.com\/online\/news\/nmr-in-target-driven-drug-discovery-why-not-new-publication-of-zobio-scientists-2\/\"},\"wordCount\":140,\"publisher\":{\"@id\":\"https:\/\/zobio.com\/online\/#organization\"},\"keywords\":[\"Discovery\"],\"articleSection\":[\"News\"],\"inLanguage\":\"en-GB\"},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/zobio.com\/online\/news\/nmr-in-target-driven-drug-discovery-why-not-new-publication-of-zobio-scientists-2\/\",\"url\":\"https:\/\/zobio.com\/online\/news\/nmr-in-target-driven-drug-discovery-why-not-new-publication-of-zobio-scientists-2\/\",\"name\":\"NMR in Target Driven Drug Discovery: Why Not? 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