{"id":1969,"date":"2020-09-07T09:08:04","date_gmt":"2020-09-07T09:08:04","guid":{"rendered":"https:\/\/zobio.com\/?p=1969"},"modified":"2025-01-21T15:17:52","modified_gmt":"2025-01-21T15:17:52","slug":"mirati-and-zobio-collaborate-to-advance-targeted-oncology-programs","status":"publish","type":"post","link":"https:\/\/zobio.com\/online\/news\/mirati-and-zobio-collaborate-to-advance-targeted-oncology-programs\/","title":{"rendered":"Mirati and ZoBio Collaborate to Advance Targeted Oncology Programs"},"content":{"rendered":"

Mirati and ZoBio Collaborate to Advance Targeted Oncology Programs<\/h2>\n
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Mirati Therapeutics has selected ZoBio to provide fragment-based screening, biophysical compound characterization and structural biology for several oncology targets. In this arrangement, ZoBio screens its fragment library using both its proprietary Target Immobilized NMR Screening and SPR capabilities. Subsequently hit analogs are characterized by a biophysics-based cascade tailored to select molecules with the desired Mode of Action and binding site. Medicinal chemistry decision making is aided by ZoBio\u2019s unique combination of solution NMR and X-ray crystallography that provides structural information earlier, particularly for weakly binding fragment hits and early analogs.<\/p>\n

Statement from Matt Marx and Gregg Siegal: \u201cWe are excited to be working together to advance Mirati\u2019s preclinical portfolio.\u00a0 This represents an ideal combination of Mirati\u2019s discovery expertise and approach to target selection and ZoBio\u2019s platform of capabilities and proven track record in hit identification, characterization and target enablement.\u201c<\/i><\/p>\n<\/div>\n<\/div><\/div><\/div>

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 <\/p>\n<\/div>\n<\/div><\/div><\/div><\/div><\/div><\/div><\/div>","protected":false},"excerpt":{"rendered":"

Mirati Therapeutics has selected ZoBio to provide fragment-based screening, biophysical compound characterization and structural biology for several oncology targets. In this arrangement, ZoBio screens its fragment library using both its proprietary Target Immobilized NMR Screening and SPR capabilities…<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"gpsa_enabled":false,"gpsa_required_form_ids":[],"gpsa_require_unique_form_submission":false,"gpsa_access_behavior":"show_message","gpsa_form_redirect_path":"","gpsa_requires_access_message":"","gpsa_access":[],"gpsa_content_loading_message":"","footnotes":""},"categories":[3],"tags":[8],"class_list":["post-1969","post","type-post","status-publish","format-standard","hentry","category-news","tag-zobio"],"yoast_head":"\nMirati and ZoBio Collaborate to Advance Targeted Oncology Programs - ZoBio - Drug Discovery Technology<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/zobio.com\/online\/news\/mirati-and-zobio-collaborate-to-advance-targeted-oncology-programs\/\" \/>\n<meta property=\"og:locale\" content=\"en_GB\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Mirati and ZoBio Collaborate to Advance Targeted Oncology Programs - ZoBio - Drug Discovery Technology\" \/>\n<meta property=\"og:description\" content=\"Mirati Therapeutics has selected ZoBio to provide fragment-based screening, biophysical compound characterization and structural biology for several oncology targets. 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